News
January 3, 2025
Breakthrough in understanding tRNA processing in human cells
A research collaboration between Kate Bohnsack and Hauke Hillen, has uncovered the molecular mechanism by which the 3′-ends of transfer RNAs (tRNAs) are processed in human cells.
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September 25, 2024
Dennis Wicke receives the prize for the best doctoral thesis of the Göttingen Center for Molecular Biology. Congratulations
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September 25, 2024
Award for the best presentation of SFB member Christoph Elfman at the VAAM conference – Congratulations
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July 17, 2024
Insights into the unique biogenesis of human mitoribosomes
The assembly of human mitoribosomes takes place in modules. This surprising result is the outcome of teamwork by CRC members Ricarda Richter-Dennerlein and Henning Urlaub and the MPI Göttingen. Their study provides a detailed overview of the biogenesis of human mitochondrial ribosomes (mitoribosomes) and shows that the biogenesis of these ribosomes is characterized by the formation of protein modules that are then assembled onto ribosomal RNA.
In addition to this comprehensive roadmap, the study highlights their evolutionary divergence from bacterial and cytosolic counterparts and provides an answer to the question of how the coordination of two genomes might occur.
July 12, 2024
The SFB is getting a new member
Ricarda Richter-Dennerlein has been accepted as a new member of the SFB1565. With her subproject “The interplay of mitochondrial ribosomes and the quality control machinery during ribosome rescue”, she will bring the whole project a decisive step closer to our goal of research. We are looking forward to welcoming her. A warm welcome!
June 20, 2024
Key Function of Antisense Non-Coding RNA as Gene Expression Booster Discovered
Heike Krebber’s team has discovered a previously unanswered question about the occurrence and function of antisense RNA (asRNA). They found that asRNA acts like a booster and accelerates gene expression, especially when the cell has to react quickly and flexibly to changes in the environment. This discovery explains for the first time why cells produce large amounts of asRNA.
June 4, 2024
Poster award for SFB member Manisha Walunj at the annual meeting of the RNA SOCIETY 2024. Congratulations!
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March 1, 2024
High-resolution 3D model of plant RNA polymerase sheds light on photosynthesis
In close collaboration, the team led by Hauke Hillen and Thomas Pfannschmidt has succeeded in creating high-resolution 3D images of the chloroplast copying machine (RNA polymerase PEP) using cryo-electron microscopy. The detailed structure provides new insights into the function and evolution of this cellular machine, which is crucial for the activation of photosynthetic proteins.