June 20, 2024
Heike Krebber’s team has discovered a previously unanswered question about the occurrence and function of antisense RNA (asRNA). They found that asRNA acts like a booster and accelerates gene expression, especially when the cell has to react quickly and flexibly to changes in the environment. This discovery explains for the first time why cells produce large amounts of asRNA.
June 4, 2024
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March 1, 2024
In close collaboration, the team led by Hauke Hillen and Thomas Pfannschmidt has succeeded in creating high-resolution 3D images of the chloroplast copying machine (RNA polymerase PEP) using cryo-electron microscopy. The detailed structure provides new insights into the function and evolution of this cellular machine, which is crucial for the activation of photosynthetic proteins.
February 8, 2024
Sonja Lorenz and other members of the SFB have succeeded for the first time in visualising the mode of action of a ubiquitin ligase in 3D. The ligase binds ubiquitin molecules to proteins and uses this code to determine whether the proteins are incorporated or degraded, thereby regulating numerous processes in the cell.
January 30, 2024
The 3D folding of the genome influences which genes are switched on or off. Marieke Oudelaar and Elisa Oberbeckmann have made a decisive methodological advance in understanding how the genome folds. They succeeded in reproducing chromatin from yeast. This made it possible to systematically analyse the folding process and the proteins involved and to decipher the underlying mechanisms. Their work was funded as part of the Collaborative Research Centre “SFB 1565”.
December 11, 2023
The EMBO Young Investigator Program is an initiative that not only provides financial support to excellent young group leaders in the early stages of their independent careers, but also include travel grants and mentoring opportunities.
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November 13, 2023
Professor Claudia Höbartner from the University of Würzburg, member of the SFB1565, has been awarded the Hansen Family Award by the Bayer Foundation for her groundbreaking research in functional nucleic acids. The prize, donated by Professor Hansen, former Chairman of the Board of Management and Supervisory Board of Bayer, has been awarded to scientists since 2000.
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September 5, 2023
The European Research Council (ERC) is funding three Göttingen Campus academics including Dr. Marieke Oudelaar and Prof. Dr. Hauke Hillen with an ERC Starting Grant for a period of five years.
July 20, 2023
Together with colleagues from Göttingen and Köln, SFB1565 project leader Prof. Dr. Argyris Papantonis reveals that with age the reading of genes becomes more error-prone and the quality of gene products decreases.
July 11, 2023
Prof. Dr. Claudia Höbartner has been honored by the Free State of Bavaria with the Bavarian Order of Merit 2023.
Read more: Deutsch