May 1, 2025
With her subproject “Genome-wide in vitro reconstitution of cohesin-mediated loop extrusion to understand the interplay of chromatin architecture and gene expression“ she will be of great benefit and complement the SFB. Welcome, Elisa.
January 3, 2025
A research collaboration between Kate Bohnsack and Hauke Hillen, has uncovered the molecular mechanism by which the 3′-ends of transfer RNAs (tRNAs) are processed in human cells.
Read more: English
September 25, 2024
Read more: English
September 25, 2024
Read more: English
July 17, 2024
The assembly of human mitoribosomes takes place in modules. This surprising result is the outcome of teamwork by CRC members Ricarda Richter-Dennerlein and Henning Urlaub and the MPI Göttingen. Their study provides a detailed overview of the biogenesis of human mitochondrial ribosomes (mitoribosomes) and shows that the biogenesis of these ribosomes is characterized by the formation of protein modules that are then assembled onto ribosomal RNA.
In addition to this comprehensive roadmap, the study highlights their evolutionary divergence from bacterial and cytosolic counterparts and provides an answer to the question of how the coordination of two genomes might occur.
July 12, 2024
Ricarda Richter-Dennerlein has been accepted as a new member of the SFB1565. With her subproject “The interplay of mitochondrial ribosomes and the quality control machinery during ribosome rescue”, she will bring the whole project a decisive step closer to our goal of research. We are looking forward to welcoming her. A warm welcome!