January 30, 2024
It is in our genes – and how our genome folds in 3D
The 3D folding of the genome influences which genes are switched on or off. Marieke Oudelaar and Elisa Oberbeckmann have made a decisive methodological advance in understanding how the genome folds. They succeeded in reproducing chromatin from yeast. This made it possible to systematically analyse the folding process and the proteins involved and to decipher the underlying mechanisms. Their work was funded as part of the Collaborative Research Centre “SFB 1565”.